Archive 2025

Aerospace and Defense Particle Counting

Details: Created: Tuesday, 21 October 2025 09:18

spaceship Typical ISO class cleanrooms in industries such as Pharmaceuticals or Semiconductors necessitate a standard set of demands for particle counting instrumentation and accessories to help customers achieve the required specifications outlined by regulatory committees. The Aerospace and Defense industries need to meet their own unique set of requirements that are often more variable and customer-specific than in other markets; this is something Particle Measuring Systems instrumentation and expertise can support.

Normalized Data in Microbial Continuous Monitoring

Details: Created: Tuesday, 21 October 2025 09:10

courtesy of Particle Measuring Systems

According to current guidelines for manufacturing in cleanrooms, the standard unit of measurement for quantifying active air sampling results is Colony-Forming Units per cubic meter (CFU/m³).

In grade A cleanroom environments, EU GMP Vol. 4 Annex 1 (2022 Revision) requires continuous active air monitoring for the entire duration of critical operations, including assembly/set-up phase. A similar approach should also be considered for Grade B environments:

Particle Measuring Systems and Pharma Integration Introduce the BioCapt® Single-Use AutoM

Details: Created: Monday, 22 September 2025 10:41

courtesy of Particle Measuring Systems

The BioCapt Single-Use AutoM Microbial Impactor has a unique magnetic clasp for simple use with robotic and mechanical arms, while leveraging its single-use advantages.

Particle Measuring Systems (PMS), a global leader in contamination monitoring, and Pharma Integration, a company that specializes in innovative robotic solutions for small volume fill-finishing for next-generation injectable drugs are proud to announce the launch of the BioCapt Single-Use AutoM Microbial Impactor.

This innovative product is designed to increase the reliability and repeatability of microbial air sampling readings in robotic pharmaceutical manufacturing environments. Its unique design reduces human interference in the monitoring process, or even eliminates it when used with robotics. The magnetic lid design of the plate ensures secure sealing, and correct and safe manipulation, streamlining its integration into existing filling lines with and without robotics. Thanks to a range of accessories, it can seamlessly fit onto existing filling lines without requiring invasive modifications. The plate thus becomes ideal for microbial air monitoring in controlled environments, cleanrooms, and isolators, including gloveless ones.

MS 20 MultiScan - easy to use

Details: Created: Wednesday, 30 July 2025 13:01

MS 20 with six ST S courtesy of DataPhysics Instruments

Did you know that our MS 20 MultiScan dispersion stability analysis system is super easy to handle? In this video, we explain how to use the system - and it's really a walk in the park.
Find out more about the MS 20 MultiScan dispersion stability analysis system:

Contamination Control in Compressed Gas Systems

Details: Created: Wednesday, 30 July 2025 12:47

courtesy of Particle Measuring Systems

In the world of aseptic pharmaceutical manufacturing, the reliability and safety of utilities are paramount. Utilities can be categorized into two main types: process systems and process support systems. While process support systems do not directly impact product quality or patient safety, process systems are critical as they interact with products or essential materials. One of the most vital process systems in this context is compressed gas.

Compressed gas systems in aseptic manufacturing, including air, nitrogen, carbon dioxide, and gaseous hydrogen, play a crucial role throughout various stages of pharmaceutical processes. Therefore, understanding and managing the risks associated with these systems is essential for maintaining product quality and ensuring compliance with Good Manufacturing Practices (GMP).

Introducing the FDDS FlexDrop dosing system by DataPhysics

Details: Created: Friday, 06 June 2025 14:48

The FDDS FlexDrop dosing system is a module for the contact angle measuring devices of the OCA series.
The innovative dosing technology and precise control allow the analysis of solid surfaces with the smallest drops
in the nanolitre or picolitre range, with pinpoint accuracy and reproducibility.

The FlexDrop can be equipped with two dosing heads at the same time. This allows simultaneous measurements
on two droplets on structures as small as one square millimetre.

Need a fast way to check cleanroom contamination limits? Get your free quick-reference guide here.

Details: Created: Friday, 06 June 2025 14:38

courtesy of Particle Measuring Systems

That’s why Particle Measuring Systems has created the Cleanroom Standards At-a-Glance Cards,
a free quick-reference tool designed to help you navigate cleanroom standards with ease.

Download Your Free Cleanroom Compliance Cards Here

Studying the concentration dependency of dynamic surface tension with MBP 200

Details: Created: Wednesday, 09 April 2025 14:16

courtesy of DataPhysics

Soap Surface-active agents (surfactants) are commonly used compounds in both daily life and a wide range of industrial processes. They have a significant impact on the formation of droplets and films, which are crucial points for the quality of many products. It has been established that surfactants in solutions can react to changes in the available surface area in a matter of milliseconds,[1] which is crucial for their efficiency in washing processes or during spraying applications. It is therefore important to study the kinetics of surfactant adsorption at the gas/liquid interface, particularly for processes involving rapid wetting. Dynamic surface tension is an ideal parameter for understanding fast wetting processes. The MBP 200 Bubble Pressure Tensiometer manufactured by DataPhysics Instruments is an ideal instrument for measuring dynamic surface tension, with the capacity to determine surface tension at surface ages down to 5 milliseconds. The following application note will showcase an automatic approach to determine the dynamic surface tension of Lutensol® solutions with different concentrations.

New Tool for Material Scientists from Surface Measurment Systems

Details: Created: Wednesday, 09 April 2025 14:05

courtesy of Surface Measurement Systems

Plasma-assisted surface engineering for value added in starch bioplastics:

Details: Created: Thursday, 02 January 2025 14:17

courtesy of DataPhysics

The recent journal article ‘Plasma-assisted surface engineering for value added in starch bioplastics: A study on enhanced surface properties and natural dye’ by Bidhari Pidhatika et al. analyzes how starch-based bioplastics can be coloured using natural dyes. Thus, this study aims to support the search for sustainable alternatives to petroleum-based plastics.

This study demonstrates how plasma treatments and an additional binder can enhance stable colouration with natural dyes on starch bioplastic surfaces. Specifically, the researchers examined two natural dyes – telang and curcumin – and their performance on bioplastics made from cassava. They found that curcumin adhered well to the bioplastic surface, even without plasma treatment and additional binder. Telang, on the other hand, required plasma treatment and an additional binder to adhere strongly to the surface.

Optimizing Microbial Sampling Methods in Pharma Manufacturing

Details: Created: Thursday, 02 January 2025 14:14

courtesy of Particle Measuring Systems

Mic Microbial air sampler biocapt single use impactor robial air samplers in pharmaceutical manufacturing facilities can be used via several methods:

surface microbial sampling
passive air microbial environmental sampling
active air microbial environmental sampling

Each of these microbial air sampling methods produces a result based on the growth of microbial colonies on the surface of a collection media (typically agar), but the specific instruments and techniques vary between the methods.

The results from any individual element of sampling do not constitute evidence of asepsis, so all elements of sampling should be used collectively in support of sterility assurance, as is given in the current version of EU GMP Annex 1: 2022 (Learn more about Annex 1: 2022 here)

Determination of dynamic surface tension of liquids

Details: Created: Monday, 23 December 2024 13:54

courtesy of DataPhysics

DataPhysics Instruments has expanded its product portfolio with the addition of the MBP 200 Bubble Pressure Tensiometer for measuring the dynamic surface tension of liquids. The MBP 200 is ideal for investigating processes in which liquid droplets are produced at a high speed, such as inkjet printing or spraying processes.

DataPhysics Instruments has launched the MBP 200 Bubble Pressure Tensiometer onto the market this year. The MBP 200 is a stationary laboratory instrument for the precise determination of the dynamic surface tension of liquids. Dr Sebastian Schaubach, Innovation Manager at DataPhysics Instruments, says: With the MBP 200 Bubble Pressure Tensiometer, we have been able to add an important parameter to our analysis spectrum and thus provide users with another highly specialised and high-precision measuring device in our product portfolio